Allergy Components

IgE allergen component testing may be helpful in those cases wherein clinicians need to identify and quantify the IgE levels of the parts or components of a suspected, offending allergen that trigger genuine allergic sensitization and likely severe, systemic reaction and those that may produce cross-reactive sensitization and decreased clinical responsiveness.

Knowing this information may assist with management decisions, such as1:

  • Patient risk assessment and stratification for procedures such as food challenge testing,
  • Patient counseling on allergen exposure reduction and/or avoidance, or
  • Patient selection and selection of specific allergen(s) for immunotherapy.

As with any allergy testing, it is important to stress the importance of evaluating allergen component test results within the context of the patient’s history, as allergen IgE sensitization does not necessarily equate to clinical responsiveness; and each allergic patient responds individually to exposure to various allergen sources, creating his or her own distinct IgE antibody molecular “profile”.1

Below is a listing of frequently ordered individual allergens and profiles which include component reflexes. You can read a full description of each test by clicking on the test number in the table. A complete listing of allergen component testing and profiles can be found in our allergy test menu.

Frequently Ordered Individual Allergens with Component Reflexes

Frequently Ordered Allergen Profiles with Component Reflexes

*If reflex testing is performed; additional charges/CPT code(s) may apply.

References

1. Canonica GW, Ansotegui IJ, Pawankar R et al. A WAO – ARIA – GA2LEN consensus document on molecular-based allergy diagnostics. World Allergy Organization Journal 2013,6(17)1-17.

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